Title: Vitamin D deficiency, cardiac iron and cardiac function in thalassaemia major.
Authors: Wood, John C.; Claster, Susan; Carson, Susan; Menteer, J. D.; Hofstra, Thomas;
Khanna, Rachna; Coates, Thomas
Source: British Journal of Haematology; Jun2008, Vol. 141 Issue 6, p891-894, 4p
Document Type: Article
Abstract: Vitamin D25-OH and D1-25OH levels were compared with cardiac R2* (1/T2*),
left ventricular ejection fraction (LVEF), age, ferritin and liver iron in 24 thalassaemia major patients.
Vitamin D25-OH levels were reduced in 13/24 patients while vitamin D1-25OH levels were often elevated.
Vitamin D25-OH levels decreased with age ( r2 = 0-48) and with liver iron ( r2 = 0-20).
Cardiac R2* was inversely related with the ratio of D25-OH to D1-25OH levels ( r2 = 0-42).
Title: Consensus recommendations.
Authors: Beutler, Ernest
Source: British Journal of Haematology; Sep2007, Vol. 138 Issue 6, p673-675, 3p
Document Type: Editorial
Abstract: The author reflects on the need to have reliable consensus on providing advice in medicine.
He cited the article about the recommendations on how to manage the hematological and onco-hematological
aspects of Gaucher's disease which he claimed to require careful scrutiny. He also mentioned the contribution
of Genzyme Corp. to the society.